CLIMB — CLinical Innovation in MicroBiome

Publicaciones

Publicaciones obtenidas automáticamente desde ORCID.

Beyond bacilli: integrating the microbiome into the TB research agenda — Gut Microbes (2026)
Younger age as a key predictor of follow‐up abandonment among PrEP users: A retrospective cohort study in Madrid — HIV Medicine (2026)
Clarifying INSTINCT: Switching From Dolutegravir/Lamivudine to Bictegravir/Emtricitabine/Tenofovir Shows Comparable Inflammatory and Weight Outcomes — Clinical Infectious Diseases (2026)
Interferon-Associated Inflammation and Galectin-9 Predict Risk of Non-AIDS Events and Mortality in Treated HIV (2026)
Comparable Inflammatory and Metabolic Outcomes After Switching to Bictegravir/Emtricitabine/Tenofovir Alafenamide Versus Continuing Dolutegravir/Lamivudine in Virologically Suppressed Adults With HIV (INSTINCT/GESIDA10918 Study) — Clinical Infectious Diseases (2026)
Lyophilised fecal microbiota transfer in capsules for recurrent Clostridioides difficile infection — International Journal of Antimicrobial Agents (2025)
A Phase IV, open-label, single-arm, multicentric clinical trial for evaluation of Human Papillomavirus 9vHPV vaccine immunogenicity in Men Who Have Sex with Men living with HIV: GeSIDA Study 10017 (2025)
Identification of Inflammation Markers as Novel Potential Predictors of the HIV-DNA Reservoir Size — International Journal of Molecular Sciences (2025)
Galectin 9 Levels as a Potential Predictor of Intact HIV Reservoir Decay — The Journal of Infectious Diseases (2025)
Author Correction: Microbiome-derived cobalamin and succinyl-CoA as biomarkers for improved screening of anal cancer — Nature Medicine (2024)
The Influence of Pre-Existing Immunity against Human Common Cold Coronaviruses on COVID-19 Susceptibility and Severity — Microbiology Research (2023)
From Innovation to Implementation: The Evolution of HIV Pre-Exposure Prophylaxis and Future Implications — Pathogens (2023)
Microbiome-derived cobalamin and succinyl-CoA as biomarkers for improved screening of anal cancer — Nature Medicine (2023)
CD4/CD8 Ratio During Human Immunodeficiency Virus Treatment: Time for Routine Monitoring? — Clinical Infectious Diseases (2023)
Diversity of immune responses in children highly exposed to SARS-CoV-2. — Frontiers in immunology (2023)
Corrigendum: Translating the observed differences in interleukin-6 levels between some antiretroviral regimens into potential long-term risk of serious non-AIDS events: A modeling study. — Frontiers in immunology (2023)
Metabolic-Related Outcomes After Switching From Tenofovir Disoproxil Fumarate to Tenofovir Alafenamide in Adults With Human Immunodeficiency Virus (HIV): A Multicenter Prospective Cohort Study. — Clinical infectious diseases : an official publication of the Infectious Diseases Society of America (2023)
Folliculitis decalvans has a heterogeneous microbiological signature and impaired immunological response. — Dermatology (Basel, Switzerland) (2023)
The microbiota as a modulator of mucosal inflammation and HIV/HPV pathogenesis: From association to causation. — Frontiers in immunology (2023)
Beyond Undetectable: Modeling the Clinical Benefit of Improved Antiretroviral Adherence in Persons With Human Immunodeficiency Virus With Virologic Suppression — Open Forum Infectious Diseases (2023)
Chagas disease is related to structural changes of the gut microbiota in adults with chronic infection (TRIPOBIOME Study) — PLoS Neglected Tropical Diseases (2023)
Contribution of Low CD4 Cell Counts and High Human Immunodeficiency Virus (HIV) Viral Load to the Efficacy of Preferred First-Line Antiretroviral Regimens for Treating HIV Infection: A Systematic Review and Meta-Analysis — Clinical Infectious Diseases (2023)
Differential abundance of lipids and metabolites related to SARS-CoV-2 infection and susceptibility — Scientific Reports (2023)
Editorial: Targeting the microbiota to attenuate chronic inflammation — Frontiers in Immunology (2023)
Expanding HIV Clinical Monitoring: The Role of CD4, CD8, and CD4/CD8 Ratio in Predicting Non-AIDS Events — MedRxiv (2023)
Expanding HIV clinical monitoring: the role of CD4, CD8, and CD4/CD8 ratio in predicting non-AIDS events — EBioMedicine (2023)
From Innovation to Implementation: The Evolution of HIV Pre-Exposure Prophylaxis and Future Implications — Preprints.org (2023)
Global DNA methylation and telomere length as markers of accelerated aging in people living with HIV and non-alcoholic fatty liver disease — BMC Genomics (2023)
Highlights of the first edition of the European Conference on Microbiota & Virology: A hybrid event, Paris, 23 March 2023 — Journal of Virus Eradication (2023)
How the microbiome can help detect precancerous lesions and prevent anal cancer — Nature Medicine (2023)
Microbiome-Derived Cobalamin and Succinyl-CoA are Powerful Biomarkers for Improved Screening of Anal Cancer (2022)
Translating the observed differences in interleukin-6 levels between some antiretroviral regimens into potential long-term risk of serious non-AIDS events: A modeling study. — Frontiers in immunology (2022)
Selective miRNA inhibition in CD8+ cytotoxic T lymphocytes enhances HIV-1 specific cytotoxic responses. — Frontiers in immunology (2022)
Effects of HIV Infection in Plasma Free Fatty Acid Profiles among People with Non-Alcoholic Fatty Liver Disease — Journal of Clinical Medicine (2022)
Nutritional Supplementation to Increase Influenza Vaccine Response in Children Living With HIV: A Pilot Clinical Trial. — Frontiers in pediatrics (2022)
Predictive value of CD8+ T cell and CD4/CD8 ratio at two years of successful ART in the risk of AIDS and non-AIDS events — eBioMedicine (2022)
Response to Commentary: Long-term Changes of Inflammatory Biomarkers in Individuals on Suppressive Three-Drug or Two-Drug Antiretroviral Regimens. — Frontiers in immunology (2022)
Differences in saliva ACE2 activity among infected and non-infected adult and pediatric population exposed to SARS-CoV-2. — The Journal of infection (2022)
ACE2 Serum Levels as Predictor of Infectability and Outcome in COVID-19. — Frontiers in immunology (2022)
Long-Term Changes of Inflammatory Biomarkers in Individuals on Suppressive Three-Drug or Two-Drug Antiretroviral Regimens. — Frontiers in immunology (2022)
Predictors of low-level HIV viraemia and virological failure in the era of integrase inhibitors: A Spanish nationwide cohort. — HIV medicine (2022)
Relationship of Diet to Gut Microbiota and Inflammatory Biomarkers in People with HIV — Nutrients (2022)
Similar CD4/CD8 Ratio Recovery After Initiation of Dolutegravir Plus Lamivudine Versus Dolutegravir or Bictegravir-Based Three-Drug Regimens in Naive Adults With HIV. — Frontiers in immunology (2022)
Metabolic Snapshot of Plasma Samples Reveals New Pathways Implicated in SARS-CoV-2 Pathogenesis. — Journal of proteome research (2022)
Targeting the Gut Microbiota of Vertically HIV-Infected Children to Decrease Inflammation and Immunoactivation: A Pilot Clinical Trial — Nutrients (2022)
A Summary of the Sixth International Workshop on Microbiome in HIV Pathogenesis, Prevention, and Treatment. — AIDS research and human retroviruses (2022)
Interactions among the mycobiome, bacteriome, inflammation, and diet in people living with HIV. — Gut microbes (2022)
Comparison of the efficacy of preferred antiretroviral regimens in patients with CD4 cell counts <200 versus 200/L or VL >100 000 versus 100 000 copies/mL: a systematic review with meta-analysis. GESIDA-11520 Study — Journal of the International AIDS Society (2022)
Effects of advanced HIV disease on inflammation following ART initiation — Journal of the International AIDS Society (2022)
Knowledge, attitudes, and practices in chronic inflammation and cardiovascular risk associated with HIV infection in Spain — Journal of the International AIDS Society (2022)
Metabolic-related outcomes after switching from tenofovir disoproxil fumarate to tenofovir alafenamide in adults living with HIV: a multicentre prospective cohort study — Journal of the International AIDS Society (2022)
New-onset diabetes in persons with HIV on BIC/FTC/TAF in real-world clinical practice — Journal of the International AIDS Society (2022)
How do women living with HIV experience menopause? Menopausal symptoms, anxiety and depression according to reproductive age in a multicenter cohort. — BMC women's health (2021)
Flow cytometry multiplexed method for the detection of neutralizing human antibodies to the native SARS‐CoV‐2 spike protein — EMBO Molecular Medicine (2021)
Fecal microbiota transplantation in HIV: A pilot placebo-controlled study — Nature Communications (2021)
A Retrospective Analysis of Long-Term Changes of Inflammatory Biomarkers in Individuals on Suppressive Three-Drug or Two-Drug Antiretroviral Regimens (2021)
Androgen receptor genetic variant predicts COVID-19 disease severity: a prospective longitudinal study of hospitalized COVID-19 male patients — Journal of the European Academy of Dermatology and Venereology (2021)
Anti-androgens may protect against severe COVID-19 outcomes: results from a prospective cohort study of 77 hospitalized men — Journal of the European Academy of Dermatology and Venereology (2021)
Anti-androgens may protect against severe COVID-19 outcomes: results from a prospective cohort study of 77 hospitalized men — Journal of the European Academy of Dermatology and Venereology (2021)
Blood bacterial profiles associated with human immunodeficiency virus infection and immune recovery — Journal of Infectious Diseases (2021)
CD4+:CD8+ T-cell ratio changes in people with HIV receiving antiretroviral treatment — Antiviral Therapy (2021)
COVID-19 and geographical area of origin — Clinical Microbiology and Infection (2021)
Effect of the use of galectin-9 and blockade of the TIM-3 receptor in the latent cellular reservoir of HIV-1 — Journal of Virology (2021)
Effects of Two-Drug Regimens of Antiretroviral Therapy on Inflammatory Biomarkers in CoRIS: A Prospective Nested Cohort Study (2021)
Effects of first- line anti-retroviral therapy on the CD4/CD8 ratio and CD8 cell counts in CoRIS: a prospective multicentre cohort study (vol 7, pg e567, 2020) — The Lancet HIV (2021)
Effects of tocilizumab on mortality in hospitalized patients with COVID-19: a multicentre cohort study — Clinical Microbiology and Infection (2021)
Exploiting the Microbiota for the Diagnosis of Anal Precancerous Lesions in Men Who Have Sex with Men — Journal of Infectious Diseases (2021)
Folliculitis decalvans microbiologic signature is specific for disease clinical phenotype — Journal of the American Academy of Dermatology (2021)
Impact of first-line antiretroviral therapy regimens on the restoration of the CD4/CD8 ratio in the CNICS cohort — Journal of Antimicrobial Chemotherapy (2021)
Implementation of a lung cancer screening initiative in HIV-infected subjects — PLoS ONE (2021)
Management of Comorbidities in Treated HIV Infection: A Long Way to Go: HIV, comorbidities and aging — International Journal of Antimicrobial Agents (2021)
Metabolic snapshot of plasma samples reveals new pathways implicated in SARS-CoV-2 pathogenesis — bioRxiv (2021)
Role of ACE2 genetic polymorphisms in susceptibility to SARS-CoV-2 among highly exposed but non infected healthcare workers — Emerging Microbes and Infections (2021)
Sarilumab in patients admitted to hospital with severe or critical COVID-19: a randomised, double-blind, placebo-controlled, phase 3 trial — The Lancet Respiratory Medicine (2021)
The potential clinical impact of the observed differences in IL-6, a marker of inflammation, associated with some antiretroviral regimens — HIV Medicine (2021)
Weight changes after antiretroviral therapy initiation in CoRIS (Spain): a prospective multicentre cohort study — Journal of the International AIDS Society (2021)
Effectiveness and safety of first-line antiretroviral regimens in clinical practice: a multicentre cohort study. — The Journal of antimicrobial chemotherapy (2020)
Analysis of the gut microbiota in alopecia areata: identification of bacterial biomarkers — Journal of the European Academy of Dermatology and Venereology (2020)
Physicians' opinions on generic antiretroviral drugs and single-tablet regimen de-simplification for the treatment of HIV infection: a multicentre survey in Spain. — The Journal of antimicrobial chemotherapy (2020)
Changes in inflammatory biomarkers in SWORD-1 and SWORD-2 studies — The Lancet HIV (2020)
Description of COVID-19 in HIV-infected individuals: a single-centre, prospective cohort — The Lancet HIV (2020)
Effect of a nutritional intervention on the intestinal microbiota of vertically hiv-infected children: The pediabiota study — Nutrients (2020)
Effectiveness of the combination elvitegravir/cobicistat/tenofovir/emtricitabine (EVG/COB/TFV/FTC) plus darunavir among treatment-experienced patients in clinical practice: A multicentre cohort study — AIDS Research and Therapy (2020)
Effects of Tocilizumab on Mortality in Hospitalized Patients with COVID-19: A Multicenter Cohort Study — medRxiv (2020)
Effects of first-line antiretroviral therapy on the CD4/CD8 ratio and CD8 cell counts in CoRIS: a prospective multicentre cohort study — The Lancet HIV (2020)
Flow cytometry multiplexed method for the Detection of neutralizing human Antibodies to the native SARS-CoV-2 spike protein — medRxiv (2020)
Pneumococcal vaccination in adult people living with HIV on suppressive antiretroviral therapy: a case–control study — International Journal of STD and AIDS (2020)
Possible role of HLA class-I genotype in SARS-CoV-2 infection and progression: A pilot study in a cohort of Covid-19 Spanish patients — Clinical Immunology (2020)
Reducing ART to less than 3-ARV regimen linked to increased systemic inflammation — Journal of the International AIDS Society (2020)
The Impact of Human Immunodeficiency Virus Infection on Gut Microbiota α-Diversity: An Individual-level Meta-analysis — Clinical Infectious Diseases (2020)
Travelling with HIV in the XXI century: Case report and narrative review — Travel Medicine and Infectious Disease (2020)
Understanding clinical decision-making during the COVID-19 pandemic: A cross-sectional worldwide survey — EClinicalMedicine (2020)
Modulation of Saliva Microbiota through Prebiotic Intervention in HIV-Infected Individuals — Nutrients (2019)
Atraumatic Incomplete Sternal Fracture Incidentally Detected in a Human Immunodeficiency Virus Patient at Lung Cancer Screening with Low-Dose Thoracic CT — Journal of Clinical Rheumatology (2019)
Delayed gastrointestinal-Associated lymphoid tissue reconstitution in duodenum compared with rectum in HIV-infected patients initiating antiretroviral therapy — AIDS (2019)
Effects of immunonutrition in advanced human immunodeficiency virus disease: A randomized placebo-controlled clinical trial (Promaltia study) — Clinical Infectious Diseases (2019)
Evaluation of kidney function in HIV-infected patients receiving an antiretroviral regimen containing one or two inhibitors of the tubular secretion of creatinine — HIV Medicine (2019)
HIV, cancer, and the microbiota: Common pathways influencing different diseases — Frontiers in Immunology (2019)
Reply to Taramasso et al — Clinical Infectious Diseases (2019)
[HIV in Spain 2017: policies for a new management of chronicity beyond virological control]. — Revista espanola de salud publica (2018)
Interplay between gut microbiota metabolism and inflammation in HIV infection — The ISME Journal (2018)
Effects of HIV, antiretroviral therapy and prebiotics on the active fraction of the gut microbiota — AIDS (2018)
Erratum: Effects of immunonutrition in advanced human immunodeficiency virus disease: A randomized placebo-controlled clinical trial (Promaltia study) (Clinical Infectious Diseases DOI: 10.1093/cid/ciy414) — Clinical Infectious Diseases (2018)
HIV in Spain 2017: Policies for a new management of chronicity beyond virological control,VIH en España 2017: Políticas para una nueva gestión de la cronicidad más allá del control virológico — Revista Espanola de Salud Publica (2018)
HIV in Spain 2017: policies for a new management of chronicity beyond virological control — Revista Española de Salud Pública (2018)
Maraviroc is associated with latent HIV-1 reactivation through NF-κB activation in resting CD4 + T cells from HIVinfected individuals on suppressive antiretroviral therapy — Journal of Virology (2018)
The functional consequences of the microbiome in HIV: Insights from metabolomic studies — Current Opinion in HIV and AIDS (2018)
Screening for precancerous anal lesions with P16/Ki67 immunostaining in HIV-infected MSM — PLOS ONE (2017)
Correction: Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naïve to Antiretroviral Therapy: A Pilot Randomized Trial. — PLoS pathogens (2017)
Concordance of Barthel Index, ECOG-PS, and Palliative Performance Scale in the assessment of functional status in patients with advanced medical diseases. — BMJ supportive & palliative care (2017)
Different impact of raltegravir versus efavirenz on CD4/CD8 ratio recovery in HIV-infected patients — Journal of Antimicrobial Chemotherapy (2017)
Effects of maraviroc versus efavirenz in combination with zidovudine-lamivudine on the CD4/CD8 ratio in treatment-naive HIV-infected individuals — Antimicrobial Agents and Chemotherapy (2017)
HIV, HPV, and microbiota: Partners in crime? — AIDS (2017)
How can the gut microbiota affect immune recovery in HIV-infected individuals? — Future Microbiology (2017)
The effects of prebiotics on microbial dysbiosis, butyrate production and immunity in HIV-infected subjects — Mucosal Immunology (2017)
Tissue Pharmacologic and Virologic Determinants of Duodenal and Rectal Gastrointestinal-Associated Lymphoid Tissue Immune Reconstitution in HIV-Infected Patients Initiating Antiretroviral Therapy — Journal of Infectious Diseases (2017)
International Congress of Drug Therapy in HIV Infection 23-26 October 2016, Glasgow, UK. — Journal of the International AIDS Society (2016)
Different impact of raltegravir versus efavirenz on CD4/CD8 ratio recovery in HIV-infected patients. (2016)
Oral anticoagulation in patients with atrial fibrillation and medical non-neoplastic disease in a terminal stage. (2016)
IL-15 promotes activation and expansion of CD8+ T cells in HIV-1 infection. (2016)
Prevalence of Elevated Blood Pressure in HIV-infected Children, Adolescents and Young Adults. (2016)
Bryostatin-1 for latent virus reactivation in HIV-infected patients on antiretroviral therapy. (2016)
Gut Bacteria Metabolism Impacts Immune Recovery in HIV-infected Individuals — EBioMedicine (2016)
Human Immunodeficiency Virus as a Chronic Disease: Evaluation and Management of Nonacquired Immune Deficiency Syndrome-Defining Conditions. (2016)
Correction: Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naive to Antiretroviral Therapy: A Pilot Randomized Trial. (2016)
Effects of Combined CCR5/Integrase Inhibitors-Based Regimen on Mucosal Immunity in HIV-Infected Patients Naive to Antiretroviral Therapy: A Pilot Randomized Trial. (2016)
Beyond Undetectable Viral Load: Effect of Nucleotides on Inflammation — EBioMedicine (2016)
Discontinuation of dolutegravir (DTG)-based regimens in clinical practice — Journal of the International AIDS Society (2016)
HIV infection results in metabolic alterations in the gut microbiota different from those induced by other diseases. (2016)
Altered metabolism of gut microbiota contributes to chronic immune activation in HIV-infected individuals. (2015)
Decreasing prevalence of HCV coinfection in all risk groups for HIV infection between 2004 and 2011 in Spain — Journal of Viral Hepatitis (2015)
CD4/CD8 ratio: an emerging biomarker for HIV. (2015)
[Reply]. (2015)
IL-15 drives CD8 T cell cycling and differentiation in chronic HIV-1 infection — The Journal of Immunology (2015)
Monitoring the CD4/CD8 ratio: A promising indicator of disease progression in HIV-infected individuals? — Future Virology (2015)
Infections caused by carbapenemase-producing Enterobacteriaceae: risk factors, clinical features and prognosis. (2014)
Development of tuberculosis in human immunodeficiency virus infected patients receiving antiretroviral therapy. (2014)
Functionally defective high-density lipoproteins are related to heightened T-cell activation in vertically HIV-infected adolescents. (2014)
Diagnosis of subclinical atherosclerosis in HIV-infected patients: higher accuracy of the D:A:D risk equation over Framingham and SCORE algorithms. (2014)
HIV-infected individuals with low CD4/CD8 ratio despite effective antiretroviral therapy exhibit altered T cell subsets, heightened CD8+ T cell activation, and increased risk of non-AIDS morbidity and mortality. (2014)
Cardiovascular biomarkers in vertically HIV-infected children without metabolic abnormalities. (2014)
Development of a six-month prognostic index in patients with advanced chronic medical conditions: the PALIAR score. (2014)
Subclinical atherosclerosis and markers of immune activation in HIV-infected children and adolescents: the CaroVIH Study. (2014)
The CD4:CD8 ratio is associated with markers of age-associated disease in virally suppressed HIV-infected patients with immunological recovery. (2014)
Incidence of hepatitis C virus (HCV) in a multicenter cohort of HIV-positive patients in Spain 2004-2011: increasing rates of HCV diagnosis but not of HCV seroconversions. (2014)
Increased risk of serious non-AIDS-related events in HIV-infected subjects on antiretroviral therapy associated with a low CD4/CD8 ratio. (2014)
Dynamics of the HIV-1 latent reservoir after discontinuation of the intensification of antiretroviral treatment: results of two clinical trials. (2013)
Neutropenia during therapy with peginterferon and ribavirin in HIV-infected subjects with chronic hepatitis C and the risk of infections. (2013)
The CD4/CD8 ratio as a marker T-cell activation, senescence and activation/exhaustion in treated HIV-infected children and young adults. (2013)
Authors' Reply: association of HIV-infection and antiretroviral therapy with levels of endothelial progenitor cells and subclinical atherosclerosis. (2013)
The CD4/CD8 ratio in HIV-infected subjects is independently associated with T-cell activation despite long-term viral suppression. (2013)
[Stroke in the very old: myths and realities]. (2013)
Association of HIV-Infection and antiretroviral therapy with levels of endothelial progenitor cells and subclinical atherosclerosis. (2012)
The role of artesunate for the treatment of urinary schistosomiasis in schoolchildren: a systematic review and meta-analysis. (2012)
[Clinical factors and biomarkers associated with subclinical atherosclerosis in the human immunodeficiency virus infection]. (2012)
Incipient renal impairment as a predictor of subclinical atherosclerosis in HIV-infected patients. (2012)
[Etravirine drug interactions]. (2009)
Smoking cessation in HIV patients: rate of success and associated factors. (2009)
A 38 year old woman with hypotensive shock at the onset of menstruation: Case presentation — BMJ (Online) (2009)
A 38 year old woman with hypotensive shock at the onset of menstruation: Case progression — BMJ (Online) (2009)
A 38 year old woman with hypotensive shock at the onset of menstruation: case outcome. (2009)
Commentary: Managing clinician's assessment — BMJ (Online) (2009)
Commentary: Managing clinician's assessment. (2009)
Commentary: Patient's view — BMJ (2009)